Atropine Treatment

A low dose of atropine eye drops instilled in both eyes at bedtime has been shown in multiple studies to slow the progression of axial myopia in children. Axial myopia is the result of an excessive increase in the length of the eyeball relative to the focusing power of the lens and cornea. It is the most common type of school-aged myopia.

The original hypothesis behind atropine eye drops for myopia control was that they worked by disabling the accommodative system. However, experimental models have shown that the effect of atropine on myopia progression is not due to paralysis of accommodation.

The specific mechanism by which atropine may slow down myopia hasn’t been determined. However, recent research has shown that atropine may slow down the progression of myopia. It does so by acting on certain receptors in the back of the eye, such as retina, RPE, choroid and sclera.
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This information is provided by allaboutvision.com.